LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways

Open Access

Peer-reviewed

Research Article

Benoit Langlois,

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
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Gwenn Perrot,

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
⨯
Christophe Schneider,

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
⨯
Patrick Henriet,

Affiliation Cell Biology Unit, de Duve Institute and Université Catholique de Louvain, Brussels, Belgium
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Hervé Emonard,

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
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Laurent Martiny,

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
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Stéphane Dedieu

* E-mail: stephane.dedieu@univ-reims.fr

Affiliation Université de Reims Champagne-Ardenne, CNRS UMR 6237 MEDyC, Laboratoire SiRMa, Campus Moulin de la Housse, Reims, France
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Reader Comments

Excellent paper and new convincing evidence regarding cancer-specific signaling events regulated by LRP receptor.

No competing interests declared.

MAPK signaling cascades
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Carcinoma
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ERK signaling cascade
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Immunoprecipitation
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c-Jun N-terminal kinase signaling cascade
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Phosphorylation
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Invasive tumors
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Cancers and neoplasms
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