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closeIs Sleep Apnea associated with mortality....?
Posted by peretzl on 14 Aug 2013 at 08:53 GMT
I read with interest Ge et al paper presenting meta-analysis of 6 sleep apnea mortality studies. I found however some confusing inconsistencies in their discussion section that should be clarified.
On page 5 (left column) we read that "Severe OSA was associated with an increase in all-cause mortality compared without OSA subjects....HR 1.90...." while on the right column we read that "Severe OSA was associated with an increase in all-cause mortality compared to subjects without OSA HR 2.65.....). I guess that the HR of 2.65 referred to cardiovascular mortality but this should be corrected.
On page 7 (left Column) we read that "The current meta-analysis suggested that CPAP treatment was not associated with decrease cardiovascular mortality...compared with healthy subjects.” While in the last paragraph of the paper we read that "CPAP treatment was associated with decrease cardiovascular mortality in OSA patients.” Although the first sentence refer to a comparison with healthy subjects, it is confusing because there is no reason to assume that CPAP should decrease cardiovascular mortality in comparison with healthy subjects.