General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

Hui Wang; Daniel P. Raleigh

doi:10.1371/journal.pone.0104023

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Open Access

Peer-reviewed

Research Article

General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

Hui Wang,

Affiliation Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America
⨯
Daniel P. Raleigh

* E-mail: daniel.raleigh@stonybrook.edu

Affiliations Department of Chemistry, Stony Brook University, Stony Brook, New York, United States of America, Graduate Program in Biochemistry and Structural Biology, Graduate Program in Biophysics, Stony Brook University, Stony Brook, New York, United States of America
⨯

General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

Hui Wang,
Daniel P. Raleigh

Published: September 26, 2014
https://doi.org/10.1371/journal.pone.0104023

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Amyloid inhibitors

Posted by aluman on 31 Oct 2014 at 10:40 GMT

The most effective inhibitor of the formation of beta sheets of amyloid, and especially for IAPP, ProIAPP and amyoid beta 42 is copper (Cu(II).
For example, http://www.hoajonline.com... and
http://www.nature.com/sre...

Surprising that copper is not mentioned herein?

No competing interests declared.

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General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

General Amyloid Inhibitors? A Critical Examination of the Inhibition of IAPP Amyloid Formation by Inositol Stereoisomers

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Amyloid inhibitors

Posted by aluman on 31 Oct 2014 at 10:40 GMT