Reader Comments
Post a new comment on this article
Post Your Discussion Comment
Please follow our guidelines for comments and review our competing interests policy. Comments that do not conform to our guidelines will be promptly removed and the user account disabled. The following must be avoided:
- Remarks that could be interpreted as allegations of misconduct
- Unsupported assertions or statements
- Inflammatory or insulting language
Thank You!
Thank you for taking the time to flag this posting; we review flagged postings on a regular basis.
closeAnalog Signaling Networks
Posted by ArtK on 21 May 2009 at 14:53 GMT
http://artksthoughts.blog...
(Trackback)
I should note that my blog post expresses discomfort with the use of the word "cascade" as a false analogy, and also questions whether we can be sure that we have a "switch" here rather than a knob"
To extract a quote[1]:
"Whether evolution has fashioned digital devices on a large scale is still a matter of debate, but considering that our current technological mind set is digital, we may be inadvertently focusing too much attention on the possibility of a digitally driven biological cell. [...] Given the flexibility of analog and its inherent ability to condense data handling to a far greater degree than its digital counterpart, we think that the argument that evolution has selected largely for analog-based signaling networks is a strong one."
1. Herbert M. Sauroa,b and Boris N. Kholodenko: Quantitative analysis ofsignaling networks, Progress in Biophysics & Molecular Biology 86 (2004) 5–43,
doi:10.1016/j.pbiomolbio.2004.03.002
http://www.informatics.in...