High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

Liang Han; Qingyong Ma; Junhui Li; Han Liu; Wei Li; Guodong Ma; Qinhong Xu; Shuang Zhou; Erxi Wu

doi:10.1371/journal.pone.0027074

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Open Access

Peer-reviewed

Research Article

High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

Liang Han,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Qingyong Ma ,

* E-mail: qyma56@mail.xjtu.edu.cn

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Junhui Li,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Han Liu,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Wei Li,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Guodong Ma,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Qinhong Xu,

Affiliation Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
⨯
Shuang Zhou,

Affiliation Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota, United States of America
⨯
Erxi Wu

Affiliation Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota, United States of America
⨯

High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

Liang Han,
Qingyong Ma,
Junhui Li,
Han Liu,
Wei Li,
Guodong Ma,
Qinhong Xu,
Shuang Zhou,
Erxi Wu

Published: November 8, 2011
https://doi.org/10.1371/journal.pone.0027074

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 18 Nov 2011 at 21:17 GMT

The following article represents some of the media coverage that has occurred for this paper:

Publication: North Dakota State University
Title: “Pharmaceutical sciences researchers to publish paper - NDSU news (NDSU)”
http://www.ndsu.edu/news/...

If you see any additional coverage of this paper in the press or blogosphere, please reply to this thread and add the link to the article.

Competing interests declared: PLoS ONE Staff

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Glucose
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Cell proliferation
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Diabetes mellitus
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Transactivation
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Breast cancer
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Phosphorylation
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Antibody therapy
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High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

High Glucose Promotes Pancreatic Cancer Cell Proliferation via the Induction of EGF Expression and Transactivation of EGFR

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Media Coverage of This Article

Posted by PLOS_ONE_Group on 18 Nov 2011 at 21:17 GMT