Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

Audrey Bergouignan; Wendolyn S. Gozansky; Daniel W. Barry; Wayne Leitner; Paul S. MacLean; James O. Hill; Boris Draznin; Edward L. Melanson

doi:10.1371/journal.pone.0030164

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Peer-reviewed

Research Article

Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

Audrey Bergouignan,

Affiliation Center for Human Nutrition, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Wendolyn S. Gozansky,

Affiliation Division of Geriatric Medicine, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Daniel W. Barry,

Affiliation Division of General Internal Medicine, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Wayne Leitner,

Affiliation Division of Geriatric Medicine, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Paul S. MacLean,

Affiliations Center for Human Nutrition, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America, Division of Endocrinology, Metabolism, and Diabetes, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
James O. Hill,

Affiliations Division of Endocrinology, Metabolism, and Diabetes, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America, Section of Nutrition, Department of Pediatrics, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Boris Draznin,

Affiliation Division of Geriatric Medicine, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯
Edward L. Melanson

* E-mail: Ed.melanson@ucdenver.edu

Affiliations Center for Human Nutrition, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America, Division of Endocrinology, Metabolism, and Diabetes, School of Medicine, University of Colorado Denver, Denver, Colorado, United States of America
⨯

Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

Audrey Bergouignan,
Wendolyn S. Gozansky,
Daniel W. Barry,
Wayne Leitner,
Paul S. MacLean,
James O. Hill,
Boris Draznin,
Edward L. Melanson

Published: January 12, 2012
https://doi.org/10.1371/journal.pone.0030164

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Correction to figure 4

Posted by melansoned on 23 Mar 2012 at 17:11 GMT

Mean (± SE) total (Top) and acetylated (Bottom) PGC1α protein (Bottom) during LF (black bars) and HF (grey bars) in LN (N = 5) and OB (N = 6).
http://plosone.org/article/info:doi/10.1371/journal.pone.0030164#pone-0030164-g004

The bar graphs for total PGC1a protein are incorrect. The correct means (SE) are listed below. A new graph can be provided. There are still no significant effects of group or condition, so interpretation of results are the same, and revisions to the text are not required

LF HF
Lean 0.415 (0.010) 0.378 (0.015)
Obese 0.539 (0.106) 0.530 (0.107)

No competing interests declared.

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Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

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Correction to figure 4

Posted by melansoned on 23 Mar 2012 at 17:11 GMT