Nicotinamide Exacerbates Hypoxemia in Ventilator-Induced Lung Injury Independent of Neutrophil Infiltration

• Heather D. Jones,

  Affiliations Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Jeena Yoo,

  Affiliation Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Timothy R. Crother,

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Pierre Kyme,

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Anat Ben-Shlomo,

  Affiliation Pituitary Center, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, United States of America

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• Ramtin Khalafi,

  Affiliation Pituitary Center, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, United States of America

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• Ching W. Tseng,

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• William C. Parks,

  Affiliation Division of Pulmonary and Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Moshe Arditi,

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• George Y. Liu ,

  Contributed equally to this work with: George Y. Liu, Kenichi Shimada

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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• Kenichi Shimada

  Contributed equally to this work with: George Y. Liu, Kenichi Shimada

  * E-mail: kenichi.shimada@cshs.org

  Affiliations Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America

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