MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

Liu Hong; Thad Sharp; Behnoush Khorsand; Carol Fischer; Steven Eliason; Ali Salem; Adil Akkouch; Kim Brogden; Brad A. Amendt

doi:10.1371/journal.pone.0160915

Loading metrics

Open Access

Peer-reviewed

Research Article

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

Liu Hong ,

* E-mail: liu-hong@uiowa.edu (LH); brad-amendt@uiowa.edu (BAA)

Affiliations Dows Institute for Dental Research, College of Dentistry, the University of Iowa, Iowa City, IA, United States of America, Center for Craniofacial Anomalies Research, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America

http://orcid.org/0000-0003-0308-5049

⨯
Thad Sharp,

Affiliation Department of Anatomy and Cell Biology, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America
⨯
Behnoush Khorsand,

Affiliation Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, the University of Iowa, Iowa City, IA, United States of America
⨯
Carol Fischer,

Affiliation Dows Institute for Dental Research, College of Dentistry, the University of Iowa, Iowa City, IA, United States of America
⨯
Steven Eliason,

Affiliations Center for Craniofacial Anomalies Research, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America, Department of Anatomy and Cell Biology, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America
⨯
Ali Salem,

Affiliation Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, the University of Iowa, Iowa City, IA, United States of America
⨯
Adil Akkouch,

Affiliation Dows Institute for Dental Research, College of Dentistry, the University of Iowa, Iowa City, IA, United States of America
⨯
Kim Brogden,

Affiliation Dows Institute for Dental Research, College of Dentistry, the University of Iowa, Iowa City, IA, United States of America
⨯
Brad A. Amendt

* E-mail: liu-hong@uiowa.edu (LH); brad-amendt@uiowa.edu (BAA)

Affiliations Dows Institute for Dental Research, College of Dentistry, the University of Iowa, Iowa City, IA, United States of America, Center for Craniofacial Anomalies Research, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America, Department of Anatomy and Cell Biology, Carver College of Medicine, the University of Iowa, Iowa City, IA, United States of America
⨯

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

Liu Hong,
Thad Sharp,
Behnoush Khorsand,
Carol Fischer,
Steven Eliason,
Ali Salem,
Adil Akkouch,
Kim Brogden,
Brad A. Amendt

Published: August 16, 2016
https://doi.org/10.1371/journal.pone.0160915

Reader Comments

Post a new comment on this article

Name correction

Posted by lhong on 18 Aug 2016 at 14:21 GMT

The full name of a co-author, Ali Salem, should be Aliasger K. Salem. Thank you.

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Periodontal ligament
Is the Subject Area "Periodontal ligament" applicable to this article?

Thanks for your feedback.
3' UTR
Is the Subject Area "3' UTR" applicable to this article?

Thanks for your feedback.
Fibroblasts
Is the Subject Area "Fibroblasts" applicable to this article?

Thanks for your feedback.
Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Luciferase
Is the Subject Area "Luciferase" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Nanoparticles
Is the Subject Area "Nanoparticles" applicable to this article?

Thanks for your feedback.

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

MicroRNA-200c Represses IL-6, IL-8, and CCL-5 Expression and Enhances Osteogenic Differentiation

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Name correction

Posted by lhong on 18 Aug 2016 at 14:21 GMT