Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

Yongcui Wang; Shilong Chen; Naiyang Deng; Yong Wang

doi:10.1371/journal.pone.0078518

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Peer-reviewed

Research Article

Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

Yongcui Wang,

Affiliation Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China
⨯
Shilong Chen,

Affiliation Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining, China
⨯
Naiyang Deng,

Affiliation College of Science, China Agricultural University, Beijing, China
⨯
Yong Wang

* E-mail: ywang@amss.ac.cn

Affiliations National Center for Mathematics and Interdisciplinary Sciences, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, China, Molecular Profiling Research Center for Drug Discovery, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan
⨯

Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

Yongcui Wang,
Shilong Chen,
Naiyang Deng,
Yong Wang

Published: November 11, 2013
https://doi.org/10.1371/journal.pone.0078518

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correction of Figure 4

Posted by wangyc1982 on 15 Nov 2013 at 21:11 GMT

Figure 4 is not the correct one, it should be about the results for leave one drug out cross-validation, and Figure 4A shows the procedure for leave one drug out cross-validation. Figure 4B shows the AUCs obtained from leave one drug out cross-validation by a barplot.

No competing interests declared.

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Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

Drug Repositioning by Kernel-Based Integration of Molecular Structure, Molecular Activity, and Phenotype Data

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correction of Figure 4

Posted by wangyc1982 on 15 Nov 2013 at 21:11 GMT