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Low testosterone mothers reduce androgen receptors in their fetuses

Posted by jamesmhoward on 14 Jun 2019 at 09:18 GMT

I suggest the findings of Nuss, et al., may be explained by low maternal testosterone and testosterone's effects on androgen receptor formation. I think low testosterone is involved in "increased pre-pregnancy weight status. A case may be made that testosterone is involved in androgen receptor formation in a fetus. It is my hypothesis that human evolution is based on increases in testosterone, the basis being that increased testosterone increases androgen receptors which increase intracelluar dehydroepiandrosterone (DHEA). (Citation at end of this comment.) It is my hypothesis that "DHEA is the Reason Breast Milk is Beneficial," http://anthropogeny.com/D... . Therefore, the offspring of these women may exhibit reduced androgen receptors because of reduced maternal testosterone. That is, the infants cannot benefit from the DHEA of breast milk which would reduce infant growth.

("Androgens in Human Evolution," Rivista di Biologia / Biology Forum 2001; 94: 345-362. If your library does not subscribe to "Rivista ... ," you may find this at: http://anthropogeny.com/A... where you may also see a chart of testosterone in humans and great apes which directly supports my hypothesis and was reported in the literature 2 years later.)

No competing interests declared.