Optimization of Ribosome Structure and Function by rRNA Base Modification

Jennifer L. Baxter-Roshek; Alexey N. Petrov; Jonathan D. Dinman

doi:10.1371/journal.pone.0000174

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Open Access

Peer-reviewed

Research Article

Optimization of Ribosome Structure and Function by rRNA Base Modification

Jennifer L. Baxter-Roshek,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯
Alexey N. Petrov,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯
Jonathan D. Dinman

*To whom correspondence should be addressed. E-mail: dinman@umd.edu

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯

Optimization of Ribosome Structure and Function by rRNA Base Modification

Jennifer L. Baxter-Roshek,
Alexey N. Petrov,
Jonathan D. Dinman

Published: January 24, 2007
https://doi.org/10.1371/journal.pone.0000174

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All modified on the base?

Posted by WayneDecatur on 29 Jan 2007 at 18:49 GMT

bases
http://plosone.org/article/info:doi/10.1371/journal.pone.0000174#article1.body1.sec3.p2

All modified bases?

RE: All modified on the base?

dinman replied to WayneDecatur on 30 Jan 2007 at 03:23 GMT

Dr. Decatur is right of course. The methylations in question are indeed to the 2'O ribose, while the pueudouridylations affect the base. I confess that I fell into the trap of using the term 'base' as a generic term for 'nucleoside'. My thanks to Wayne for pointing this error out.

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Optimization of Ribosome Structure and Function by rRNA Base Modification

Optimization of Ribosome Structure and Function by rRNA Base Modification

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All modified on the base?

Posted by WayneDecatur on 29 Jan 2007 at 18:49 GMT

RE: All modified on the base?

dinman replied to WayneDecatur on 30 Jan 2007 at 03:23 GMT