Optimization of Ribosome Structure and Function by rRNA Base Modification

Open Access

Peer-reviewed

Research Article

Jennifer L. Baxter-Roshek,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯
Alexey N. Petrov,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯
Jonathan D. Dinman

*To whom correspondence should be addressed. E-mail: dinman@umd.edu

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, United States of America
⨯

Reader Comments

rRNA base modification
http://plosone.org/article/info:doi/10.1371/journal.pone.0000174#article1.front1.article-meta1.abstract1.sec1.p1

It seems not only is base modification addressed in the form of pseudouridylation, but also sugar modification in the form of ribose methylation. Therefore shouldn't it say "base and sugar" modification in most places where "base modification" is used? For example, in the title?

Ribosomal RNA
Is the Subject Area "Ribosomal RNA" applicable to this article?

Thanks for your feedback.
Ribosomes
Is the Subject Area "Ribosomes" applicable to this article?

Thanks for your feedback.
Yeast
Is the Subject Area "Yeast" applicable to this article?

Thanks for your feedback.
Small nucleolar RNA
Is the Subject Area "Small nucleolar RNA" applicable to this article?

Thanks for your feedback.
Protein translation
Is the Subject Area "Protein translation" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.
Mutant strains
Is the Subject Area "Mutant strains" applicable to this article?

Thanks for your feedback.
RNA structure
Is the Subject Area "RNA structure" applicable to this article?

Thanks for your feedback.