Ste20-Related Proline/Alanine-Rich Kinase (SPAK) Regulated Transcriptionally by Hyperosmolarity Is Involved in Intestinal Barrier Function

Open Access

Peer-reviewed

Research Article

Yutao Yan ,

* E-mail: yyan2@emory.edu

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Guillaume Dalmasso,

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Hang Thi Thu Nguyen,

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Tracy S. Obertone,

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Shanthi V. Sitaraman,

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Didier Merlin

Affiliation Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

Reader Comments

Pretty interesting work, I am working on hyperosmolarity also. and I know hyper can transcriptional regulate some genes expression

No competing interests declared.

Transcription factors
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Colon
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Messenger RNA
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Small interfering RNA
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Mouse models
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Permeability
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Transfection
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Transcriptional control
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