High-Throughput Isolation and Mapping of C. elegans Mutants Susceptible to Pathogen Infection

Open Access

Peer-reviewed

Research Article

Laura E. Fuhrman,

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Kevin V. Shianna,

Affiliation Institute for Genome Sciences and Policy, Duke University, Durham, North Carolina, United States of America
⨯
Alejandro Aballay

* E-mail: a.aballay@duke.edu

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

Reader Comments

away from
http://plosone.org/article/info:doi/10.1371/journal.pone.0002882#article1.body1.sec2.sec3.p3

this should be toward the homozygous wild-type allele, which in this case represents the genetic background in which the mutation will be (as opposed to the mapping strain genetic background)

Caenorhabditis elegans
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Single nucleotide polymorphisms
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Salmonella enterica
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Signal amplification
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Bacterial pathogens
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Polymerase chain reaction
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Nematode infections
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Pathogens
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