Circulating miR-19a and miR-205 in Serum May Predict the Sensitivity of Luminal A Subtype of Breast Cancer Patients to Neoadjuvant Chemotherapy with Epirubicin Plus Paclitaxel

Qian Li; Mei Liu; Fei Ma; Yang Luo; Ruigang Cai; Liming Wang; Ningzhi Xu; Binghe Xu

doi:10.1371/journal.pone.0104870

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Open Access

Peer-reviewed

Research Article

Circulating miR-19a and miR-205 in Serum May Predict the Sensitivity of Luminal A Subtype of Breast Cancer Patients to Neoadjuvant Chemotherapy with Epirubicin Plus Paclitaxel

Qian Li ,

Contributed equally to this work with: Qian Li, Mei Liu

Affiliations Department of Medical Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China, Department of Tumor Chemotherapy and Radiation Sickness in Peking University Third Hospital, Beijing, China
⨯
Mei Liu ,

Contributed equally to this work with: Qian Li, Mei Liu

Affiliation Laboratory of Cell and Molecular Biology & State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Fei Ma,

Affiliation Department of Medical Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Yang Luo,

Affiliation Department of Medical Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Ruigang Cai,

Affiliation Department of Medical Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Liming Wang,

Affiliation Department of Abdominal Surgery, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Ningzhi Xu,

Affiliation Laboratory of Cell and Molecular Biology & State Key Laboratory of Molecular Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯
Binghe Xu

* E-mail: bhxu@hotmail.com

Affiliation Department of Medical Oncology, Cancer Institute and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China
⨯

Circulating miR-19a and miR-205 in Serum May Predict the Sensitivity of Luminal A Subtype of Breast Cancer Patients to Neoadjuvant Chemotherapy with Epirubicin Plus Paclitaxel

Qian Li,
Mei Liu,
Fei Ma,
Yang Luo,
Ruigang Cai,
Liming Wang,
Ningzhi Xu,
Binghe Xu

Published: August 19, 2014
https://doi.org/10.1371/journal.pone.0104870

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The 29 th reference is not relevant to the statement in the text

Posted by moweichuan on 03 Aug 2015 at 08:38 GMT

The discussion text “ Then, the increase of mutidrug resistance proteins may be one of the causes to lead resistance to chemotherapy. Besides, androgen receptor could up-regulate miR-19a and androgen receptor positive breast cancer has relatively low chemosensitivity [29].” cited the 29th reference “Mo WC, Zhang ZJ, Liu Y, Bartlett PF, He RQ (2013) Magnetic shielding accelerates the proliferation of human neuroblastoma cell by promoting G1-phase progression. PLoS One 8: e54775. doi: 10.1371/journal.pone.0054775”, which is definitely not relevant to the statement of this sentence.

No competing interests declared.

RE: The 29 th reference is not relevant to the statement in the text

meiliu replied to moweichuan on 05 Aug 2015 at 08:20 GMT

Thanks for your comment.
We are sorry for our mistake in the Reference 29.
The right reference shoule be:
Mo W, Zhang J, Li X, et al. Identification of Novel AR-Targeted MicroRNAs Mediating Androgen Signalling through Critical Pathways to Regulate Cell Viability in Prostate Cancer.PLoS One. 2013;8(2):e56592.

No competing interests declared.

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Circulating miR-19a and miR-205 in Serum May Predict the Sensitivity of Luminal A Subtype of Breast Cancer Patients to Neoadjuvant Chemotherapy with Epirubicin Plus Paclitaxel

Circulating miR-19a and miR-205 in Serum May Predict the Sensitivity of Luminal A Subtype of Breast Cancer Patients to Neoadjuvant Chemotherapy with Epirubicin Plus Paclitaxel

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The 29 th reference is not relevant to the statement in the text

Posted by moweichuan on 03 Aug 2015 at 08:38 GMT

RE: The 29 th reference is not relevant to the statement in the text

meiliu replied to moweichuan on 05 Aug 2015 at 08:20 GMT