Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population

Gaoqiang Xie; Phyo Kyaw Myint; M. Justin S. Zaman; Ying Li; Liancheng Zhao; Ping Shi; Fuxiu Ren; Yangfeng Wu

doi:10.1371/journal.pone.0074126

Loading metrics

Open Access

Peer-reviewed

Research Article

Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population

Gaoqiang Xie ,

* E-mail: gqxie72@163.com (GX); zhaolch@163.com (LZ)

Affiliation Peking University Clinical Research Institute, Beijing, People’s Republic of China
⨯
Phyo Kyaw Myint,

Affiliations School of Medicine and Dentistry, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland, United Kingdom, Norwich Research Park Cardiovascular Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom, Clinical Gerontology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, Stroke Research Group, Norfolk and Norwich University Hospital, Norwich, United Kingdom
⨯
M. Justin S. Zaman,

Affiliations Norwich Research Park Cardiovascular Research Group, Norwich Medical School, University of East Anglia, Norwich, United Kingdom, Department of Cardiology, James Paget University Hospital, Great Yarmouth, United Kingdom
⨯
Ying Li,

Affiliation Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, People’s Republic of China
⨯
Liancheng Zhao ,

* E-mail: gqxie72@163.com (GX); zhaolch@163.com (LZ)

Affiliation Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, People’s Republic of China
⨯
Ping Shi,

Affiliation Shijingshan Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Fuxiu Ren,

Affiliation Shijingshan Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Yangfeng Wu

Affiliations Peking University Clinical Research Institute, Beijing, People’s Republic of China, Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing, People’s Republic of China, The George Institute, Beijing, People’s Republic of China
⨯

Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population

Gaoqiang Xie,
Phyo Kyaw Myint,
M. Justin S. Zaman,
Ying Li,
Liancheng Zhao,
Ping Shi,
Fuxiu Ren,
Yangfeng Wu

Published: September 11, 2013
https://doi.org/10.1371/journal.pone.0074126

Reader Comments

Post a new comment on this article

Publisher's Note: Error in Discussion

Posted by PLOS_ONE_Group on 08 Nov 2013 at 23:47 GMT

In the fourth sentence of the third paragraph of the Discussion section, "AA genotype" should be "CC genotype." The sentence should read:
"We show that serum IL-10 level increases with serum IL-6 more rapidly in those with CC genotype of rs1800872 (p for interaction<0.001)"

No competing interests declared.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Ischemic stroke
Is the Subject Area "Ischemic stroke" applicable to this article?

Thanks for your feedback.
Cardiovascular disease risk
Is the Subject Area "Cardiovascular disease risk" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Blood pressure
Is the Subject Area "Blood pressure" applicable to this article?

Thanks for your feedback.
Atherosclerosis
Is the Subject Area "Atherosclerosis" applicable to this article?

Thanks for your feedback.
Cholesterol
Is the Subject Area "Cholesterol" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.

Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population

Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population

Reader Comments

Post Your Discussion Comment

Why should this posting be reviewed?

Thank You!

Publisher's Note: Error in Discussion

Posted by PLOS_ONE_Group on 08 Nov 2013 at 23:47 GMT