Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

Birgitte Lindegaard; Thine Hvid; Thomas Grøndahl; Christian Frosig; Jan Gerstoft; Pernille Hojman; Bente Klarlund Pedersen

doi:10.1371/journal.pone.0055632

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Open Access

Peer-reviewed

Research Article

Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

Birgitte Lindegaard ,

* E-mail: blm@rh.dk

Affiliations Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
⨯
Thine Hvid,

Affiliations Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark
⨯
Thomas Grøndahl,

Affiliations Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark
⨯
Christian Frosig,

Affiliations Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark, Institute of Exercise and Sport Sciences, Department of Human Physiology, Copenhagen, Denmark
⨯
Jan Gerstoft,

Affiliation Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
⨯
Pernille Hojman,

Affiliations Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
⨯
Bente Klarlund Pedersen

Affiliations Centre of Inflammation and Metabolism, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Muscle Research Centre, Rigshospitalet, Copenhagen, Denmark, Department of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark
⨯

Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

Birgitte Lindegaard,
Thine Hvid,
Thomas Grøndahl,
Christian Frosig,
Jan Gerstoft,
Pernille Hojman,
Bente Klarlund Pedersen

Published: March 22, 2013
https://doi.org/10.1371/journal.pone.0055632

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absolute mRNA levels?

Posted by vcortesm on 24 Jun 2014 at 20:26 GMT

Would you please show or comment the Ct values of muscle FGF21 in order to assess the absolute rather than relative abundance of this transcript?

No competing interests declared.

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Fibroblast growth factor
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Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

Expression of Fibroblast Growth Factor-21 in Muscle Is Associated with Lipodystrophy, Insulin Resistance and Lipid Disturbances in Patients with HIV

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absolute mRNA levels?

Posted by vcortesm on 24 Jun 2014 at 20:26 GMT