About the Authors

Haiyan Feng

Contributed equally to this work with: Haiyan Feng, Xiao Hu

Roles Conceptualization, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Pathology, Zibo First Hospital, Zibo, Shandong, China

Xiao Hu

Contributed equally to this work with: Haiyan Feng, Xiao Hu

Roles Data curation, Formal analysis, Software, Visualization

Affiliation Department of Pathology, Zibo First Hospital, Zibo, Shandong, China

Lei Zhang

Roles Formal analysis, Software, Writing – original draft

Affiliation Department of Pathology, Zibo First Hospital, Zibo, Shandong, China

Qi Zhang

Roles Investigation, Resources, Writing – original draft, Writing – review & editing

Affiliation Department of Pathology, Zibo First Hospital, Zibo, Shandong, China

Shuocun Wang

Roles Investigation, Writing – original draft, Writing – review & editing

Affiliation Shanghai Yijian Health Technology Co., Ltd., Shanghai, China

Bingqing Lv

Roles Investigation, Methodology, Writing – original draft

Affiliation Shanghai Yijian Health Technology Co., Ltd., Shanghai, China

Yufeng Zhang

Roles Investigation, Writing – original draft

Affiliation Shanghai Yijian Health Technology Co., Ltd., Shanghai, China

Dong Shi

Roles Conceptualization, Methodology, Supervision

shidong@xynetech.com (DS); zhouping@qlmu.edu.cn (PZ)

Affiliation Shanghai Yijian Health Technology Co., Ltd., Shanghai, China

Ping Zhou

Roles Conceptualization, Funding acquisition, Supervision

shidong@xynetech.com (DS); zhouping@qlmu.edu.cn (PZ)

Affiliation Department of Pathology, Zibo First Hospital, Zibo, Shandong, China

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: At the time of this research, BL, DS, SW, and YZ were employed by Shanghai Yijian Health Technology Co., Ltd. Shanghai Yijian Health Technology Co., Ltd also provided commercial funding for this research. A patent application related to the library construction methodology reported in this manuscript has been published (Patent title: “A highly efficient and rapid method for constructing specific libraries”; Publication No. CN119979668A), with authors BL and DS listed as inventors. There are no consultancies, products in development, or marketed products to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials. All other authors declare no competing interests.