About the Authors

Jill Isabelle Olydam

Roles Data curation, Formal analysis, Investigation, Resources, Visualization, Writing – original draft

j.olydam@erasmusmc.nl

Affiliation Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands

Thomas Litman

Roles Conceptualization, Formal analysis, Methodology, Resources, Supervision, Visualization, Writing – review & editing

Affiliations Research & Early Development, LEO Pharma, Ballerup, Denmark, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark

Tamar Nijsten

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands

Ilka Hoof

Roles Formal analysis, Methodology, Visualization, Writing – review & editing

Affiliations Research & Early Development, LEO Pharma, Ballerup, Denmark, Computational Biology, Research and Early Development, Novo Nordisk, Måløv, Denmark

Witte Koopmann

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliations Research & Early Development, LEO Pharma, Ballerup, Denmark, Truly Labs, Lund, Sweden

Luba Milena Pardo

Roles Formal analysis, Resources, Supervision, Visualization, Writing – review & editing

Affiliation Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands

DirkJan Hijnen

Roles Conceptualization, Resources, Supervision, Writing – original draft, Writing – review & editing

Affiliations Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands

Competing Interests

Conflict of interest LMP: is currently a consultant at Centogene GmbH. TL is shareholder of LEO Pharma A/S and TL, WK and IH are former employees of LEO Pharma A/S, which sponsored this study. DJH: investigator for AbbVie, Almirall, LEO Pharma, AstraZeneca, Novartis, Sanofi; consultancies for Abbvie, Sanofi, LEO Pharma, AstraZeneca, Novartis, Janssen, Pfizer, Lilly. The rest of the authors declare that they have no relevant conflicts of interest. This does not alter our adherence to PLOS ONE policies on sharing data and materials.