Integrative bioinformatics and machine learning identify shared molecular mechanisms and diagnostic biomarkers between Helicobacter pylori infection and atrial fibrillation

Aojian Deng; Wei Wang

doi:10.1371/journal.pone.0346038

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Open Access

Peer-reviewed

Research Article

Integrative bioinformatics and machine learning identify shared molecular mechanisms and diagnostic biomarkers between Helicobacter pylori infection and atrial fibrillation

Aojian Deng,

Roles Funding acquisition, Investigation, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

Affiliation Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, Chinas
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Wei Wang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

* E-mail: WangWei971122@163.com

Affiliation Department of Fourth Internal Medicine, The Third People's Hospital Health Care Group of Cixi, Ningbo, China

https://orcid.org/0000-0002-2100-3214

⨯

Integrative bioinformatics and machine learning identify shared molecular mechanisms and diagnostic biomarkers between Helicobacter pylori infection and atrial fibrillation

Aojian Deng,
Wei Wang

Published: April 10, 2026
https://doi.org/10.1371/journal.pone.0346038

About the Authors

Aojian Deng

Roles Funding acquisition, Investigation, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

Affiliation Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, Chinas

Wei Wang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Resources, Visualization, Writing – original draft, Writing – review & editing

* E-mail: WangWei971122@163.com

Affiliation Department of Fourth Internal Medicine, The Third People's Hospital Health Care Group of Cixi, Ningbo, China

https://orcid.org/0000-0002-2100-3214

Competing Interests

The authors have declared that no competing interests exists.

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Atrial fibrillation
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Retinoic acid
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Biomarkers
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Infectious disease control
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Genetic networks
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Gene expression
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Inflammation
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Network analysis
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