About the Authors

Jeroen C. de Jonge

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Writing – original draft

j.de.jonge@antoniusziekenhuis.nl

Affiliations Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands, Department of Neurology, St. Antonius Hospital, Nieuwegein/Utrecht, The Netherlands

Wouter M. Sluis

Roles Conceptualization, Data curation, Supervision, Writing – review & editing

Affiliation Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Hendrik Reinink

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

Affiliations Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands, Department of Neurology, Spaarne Gasthuis, Haarlem, The Netherlands

Philip Bath

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Writing – review & editing

Affiliation Stroke Trials Unit, University of Nottingham, Nottingham, United Kingdom

Lisa J Woodhouse

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Stroke Trials Unit, University of Nottingham, Nottingham, United Kingdom

Diederik van de Beek

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Amsterdam UMC, location University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, The Netherlands

Anne Hege Aamodt

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliations Department of Neurology, Oslo University Hospital, Oslo, Norway, Norway and Department of Neuromedicine and Movement science, Norwegian University of Science and Technology, Trondheim, Norway

Alfonso Ciccone

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Department of Neurology and Stroke Unit, ASST di Mantova, Mantua, Italy

Janika Kõrv

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Department of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia

Iwona Kurkowska-Jastrzebska

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation 2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland

Milani Deb-Chatterji

Roles Project administration, Writing – review & editing

Affiliation Department of Neurology, Neurovascular Center, University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany

Jesse Dawson

Roles Project administration, Writing – review & editing

Affiliation Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom

George Ntaios

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation First Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece

Götz Thomalla

Roles Conceptualization, Investigation, Project administration, Writing – review & editing

Affiliation Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

H Bart van der Worp

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Department of Neurology and Neurosurgery, Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

for the PRECIOUS investigators

PRECIOUS investigators: Please see the appendix of the publication of the main results for a list of the PRECIOUS investigators.

Competing Interests

JCdJ, WMS, HR report grants from the European Union, all paid to their institution. PMB is Stroke Association Professor of Stroke Medicine and an emeritus NIHR Senior Investigator; he has received grants from the NIHR and British Heart Foundation, and funding for consultancy from CoMind and DiaMedica. DvdB reports having received research grants from the European Union, The Netherlands for Health Research and Development, ItsMe Foundation, AMC Foundation and Roche; none related. AHA reports research grants from Boehringer Ingelheim, lectures fee from Abbvie, BMS/Pfizer, Novartis, Roche and Teva and participation in Advisory Board for Lundbeck, Abbvie and MSD; none related. AC reports grants from the European Union and Lombardy region, for research paid to his institution, and fees as consultant or lecturer from Alexxion Pharma, Daiichi Sanky, and Italfarmaco. JK reports lecturer fees from Boehringer Ingelheim, Pfizer and Servier, and travel grants from Boehringer Ingelheim and Servier, none related. MDC has received research grants from the Werner Otto Foundation, speakers honoraria from AstraZeneca and was funded by the Faculty of Medicine, University of Kiel, Germany through its Advanced Clinician Scientist Programme, all outside the submitted work. IKJ reports lectures and travel grants from Merck, Novartis and Roche, Angelini Pharma and travel grants from Boehringer Ingelheim, none related. GT report grants from the European Union, German Research Foundation, German Federal Ministry of Education and Research, German Innovation Fund for research paid to his institution, and fees as consultant or lecturer from Acandis, Alexion, Amarin, Bayer, Boehringer Ingelheim, Daiichi Sanky, BristolMyersSqibb/Pfizer, and Stryker. HBvdW reports having received grants from the European Union, the Dutch Heart Foundation, and Stryker for research, and funding for consultancy from Bayer, Boehringer Ingelheim, and TargED, all paid to his institution.