A common network of residue-residue contacts underlies interactions between peptides and HLA class II complex

Alexander E. Kister; Dmitry R. Leshchiner; Ilya Kister

doi:10.1371/journal.pone.0341970

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Open Access

Peer-reviewed

Research Article

A common network of residue-residue contacts underlies interactions between peptides and HLA class II complex

Alexander E. Kister,

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America
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Dmitry R. Leshchiner,

Roles Data curation, Formal analysis, Software, Validation, Writing – review & editing

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America
⨯
Ilya Kister

Roles Investigation, Methodology, Writing – review & editing

* E-mail: Ilya.Kister@nyulangone.org

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America

https://orcid.org/0000-0003-3549-949X

⨯

A common network of residue-residue contacts underlies interactions between peptides and HLA class II complex

Alexander E. Kister,
Dmitry R. Leshchiner,
Ilya Kister

Published: April 10, 2026
https://doi.org/10.1371/journal.pone.0341970

About the Authors

Alexander E. Kister

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America

Dmitry R. Leshchiner

Roles Data curation, Formal analysis, Software, Validation, Writing – review & editing

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America

Ilya Kister

Roles Investigation, Methodology, Writing – review & editing

* E-mail: Ilya.Kister@nyulangone.org

Affiliation Department of Neurology, New York University Grossman School of Medicine, New York, New York, United States of America

https://orcid.org/0000-0003-3549-949X

Competing Interests

The authors have declared that no competing interests exist.

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Prototypes
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Peptide mapping
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Alpha helix
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Computer software
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Crystal structure
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Sequence alignment
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Beta helix
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Protein structure
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