About the Authors

Beth Thompson

Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Beth.Thompson@liverpool.ac.uk

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Laura J. Else

Roles Supervision, Writing – review & editing

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Laura Dickinson

Roles Data curation

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Stacey Edick

Roles Investigation, Project administration

Affiliation University of Pittsburgh School of Medicine, Pittsburgh, Philadelphia, United States of America

Ashley Zyhowski

Roles Project administration

Affiliation Magee-Womens Research Institute, Pittsburgh, Philadelphia, United States of America

Ken Ho

Roles Investigation

Affiliation University of Pittsburgh School of Medicine, Pittsburgh, Philadelphia, United States of America

Leslie Meyn

Roles Data curation

Affiliations University of Pittsburgh School of Medicine, Pittsburgh, Philadelphia, United States of America, Magee-Womens Research Institute, Pittsburgh, Philadelphia, United States of America

Sujan Dilly-Penchala

Roles Data curation, Investigation

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Victoria Shaw

Roles Project administration

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Ian McGowan

Roles Conceptualization, Visualization

Affiliation Synklino A/S, Copenhagen, Denmark

Saye Khoo

Roles Supervision, Writing – review & editing

Affiliation Centre for Experimental Therapeutics, University of Liverpool, Liverpool, United Kingdom

Rhonda M. Brand

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

Affiliations University of Pittsburgh School of Medicine, Pittsburgh, Philadelphia, United States of America, Magee-Womens Research Institute, Pittsburgh, Philadelphia, United States of America

Competing Interests

S.K. has received research grants and travel bursaries from Gilead, ViiV, Merck, Bristol Myers Squibb, Boehringer Ingelheim and Janssen Pharmaceuticals. All other authors: none to declare. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. This does not alter our adherence to PLOS ONE policies on sharing data and materials.