Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Jianhui Li; Xuejiao Lv; Ying Jiang

doi:10.1371/journal.pone.0341064

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Open Access

Peer-reviewed

Research Article

Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Jianhui Li,

Roles Data curation, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Heilongjiang University of Chinese Medicine, Harbin, China
⨯
Xuejiao Lv,

Roles Conceptualization

Affiliation Heilongjiang University of Chinese Medicine, Harbin, China
⨯
Ying Jiang

Roles Writing – review & editing

* E-mail: 18846106176@163.com

Affiliations Heilongjiang University of Chinese Medicine, Harbin, China, College of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China

https://orcid.org/0000-0002-4532-9497

⨯

Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics

Jianhui Li,
Xuejiao Lv,
Ying Jiang

Published: January 29, 2026
https://doi.org/10.1371/journal.pone.0341064

About the Authors

Jianhui Li

Roles Data curation, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Heilongjiang University of Chinese Medicine, Harbin, China

Xuejiao Lv

Roles Conceptualization

Affiliation Heilongjiang University of Chinese Medicine, Harbin, China

Ying Jiang

Roles Writing – review & editing

* E-mail: 18846106176@163.com

Affiliations Heilongjiang University of Chinese Medicine, Harbin, China, College of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China

https://orcid.org/0000-0002-4532-9497

Competing Interests

The authors declare that there are no competing interests.

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Prostate cancer
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Cancer treatment
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Bone remodeling
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Endoplasmic reticulum
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Protein expression
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Bone and mineral metabolism
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Cell migration
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Proteomics
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