Complete molecular spectrum of β-globin gene mutations via direct sequencing identifies seven novel variants in β-thalassemia major

Torin Abdulaziz Sadoon; Hemin Esmael Othman

doi:10.1371/journal.pone.0336610

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Open Access

Peer-reviewed

Research Article

Complete molecular spectrum of β-globin gene mutations via direct sequencing identifies seven novel variants in β-thalassemia major

Torin Abdulaziz Sadoon ,

Contributed equally to this work with: Torin Abdulaziz Sadoon, Hemin Esmael Othman

Roles Investigation, Methodology, Resources, Writing – original draft

Affiliation Department of Medical Laboratory Technology, College of Health and Medical Technology-Shekhan, Duhok Polytechnic University, Kurdistan Region, Iraq
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Hemin Esmael Othman

Contributed equally to this work with: Torin Abdulaziz Sadoon, Hemin Esmael Othman

Roles Conceptualization, Data curation, Formal analysis, Software, Supervision, Writing – review & editing

* E-mail: hemin.othman@uod.ac

Affiliation Department of Biology, College of Science, University of Duhok, Kurdistan Region, Iraq

https://orcid.org/0000-0002-7659-4568

⨯

Complete molecular spectrum of β-globin gene mutations via direct sequencing identifies seven novel variants in β-thalassemia major

Torin Abdulaziz Sadoon,
Hemin Esmael Othman

Published: November 7, 2025
https://doi.org/10.1371/journal.pone.0336610

About the Authors

Torin Abdulaziz Sadoon

Contributed equally to this work with: Torin Abdulaziz Sadoon, Hemin Esmael Othman

Roles Investigation, Methodology, Resources, Writing – original draft

Affiliation Department of Medical Laboratory Technology, College of Health and Medical Technology-Shekhan, Duhok Polytechnic University, Kurdistan Region, Iraq

Hemin Esmael Othman

Contributed equally to this work with: Torin Abdulaziz Sadoon, Hemin Esmael Othman

Roles Conceptualization, Data curation, Formal analysis, Software, Supervision, Writing – review & editing

* E-mail: hemin.othman@uod.ac

Affiliation Department of Biology, College of Science, University of Duhok, Kurdistan Region, Iraq

https://orcid.org/0000-0002-7659-4568

Competing Interests

No conflicting interests are disclosed by the authors.

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Frameshift mutation
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Pathogens
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Mutation detection
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Mutation
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Deletion mutation
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