About the Authors

Alica Kubesch

Contributed equally to this work with: Alica Kubesch, Raul Lande

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Raul Lande

Contributed equally to this work with: Alica Kubesch, Raul Lande

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Anna Leutgöb

Roles Data curation, Formal analysis, Investigation

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Karima Farrag

Roles Investigation, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Iulia Dahmer

Roles Data curation, Formal analysis, Validation

Affiliation Goethe University Frankfurt, University Hospital, Institute of Biostatistics and Mathematical Modeling, Frankfurt, Germany

Katharina Stratmann-Vollrath

Roles Investigation, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Antje Dienethal

Roles Investigation, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Florian Alexander Michael

Roles Investigation, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Kathrin Sprinzl

Roles Investigation, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Stefan Zeuzem

Roles Funding acquisition, Resources, Writing – review & editing

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Irina Blumenstein

Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

blumenstein@em.uni-frankfurt.de

Affiliation Goethe University Frankfurt, University Hospital, Medical Clinic 1, Frankfurt, Germany

Competing Interests

Alica Kubesch reports consulting and lecturer fees from AbbVie, Celgene/BMS, Galapagos, Johnson & Johnson, Takeda, employment and scientitic collaboration from Fraunhofer Institute for Translational Medicine and Pharmacology ITMP and Fraunhofer Cluster of Excellence Immune Mediated Diseases CIMD, research funding by Sanofi and travel grants from Johnson & Johnson, AbbVie, Takeda, Galapagos and Pfizer. Raul Lande reports consulting and lecturer fees from AbbVie, Johnson & Johnson and Takeda and travel grants from Abbvie. Karima Farrag reports consulting and lecturer fees from AbbVie, Amgen, Celgene/BMS, Falk Foundation e.V., Johnson & Johnson, MSD International and Takeda and travel grants from Johnson & Johnson, Pharmacosmos and Lilly. Kathrin Sprinzl reports consulting fees and lecturer fees from AbbVie, Chemomab, Gilead, Ipsen, MSD and project funding from Gilead; Florian Alexander Michael reports lecutre fees from Pentax Medical and Dr. Weigert GmBH; Stefan Zeuzem reports consultancy and speaker’s bureau fees from Abbvie, Allergan, Bi-oMarin, Gilead, Intercept, Johnson & Johnson, MSD/Merck, Novo Nordisk, SoBi, and Theratechnologies; Irina Blumenstein reports consulting and lecturer fees from Abbvie, Amgen, Biogen, Celgene/BMS, Celltrion, Falk Foundation, Fresenius Kabi, Galapagos, Johnson & Johnson, Lilly, Pharmacosmos, Pfizer, Takeda, employment and scientitic collaboration from Fraunhofer Institute for Translational Medicine and Pharmacology ITMP and Fraunhofer Cluster of Excellence Immune Mediated Diseases CIMD. and travel grants from Pfizer, Johnson & Johnson, Lilly and Takeda. All other authors have no conflict of interest to disclose. There are no patents, products in development or marketed products associated with this research to declare. None of the commercial sources mentioned has any direct influence on the research focus, study design, or even the creation of the manuscript. The lecturer, consulting, or speaker’s bureau fees relate to other services that are not related to the current manuscript. The current study was financed without direct third-party funding.