About the Authors

Sayaka Kimura-Uchida

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Ryuichi Shimada

Roles Data curation, Formal analysis, Software, Validation

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Hiroshi Horiguchi

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Writing – review & editing

hhiro@jikei.ac.jp

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Satoshi Katagiri

Roles Investigation, Writing – original draft

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Hisato Gunji

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Tadashi Nakano

Roles Funding acquisition, Resources, Supervision, Writing – review & editing

Affiliation Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan

Competing Interests

The present study was supported only by the Japan Society for the Promotion of Science (JSPS KAKENHI, JP21K09729 to H.H.). Dr. Tadashi Nakano has received research funding from Alcon Japan Ltd., Santen Pharmaceutical Co., Ltd., Senju Pharmaceutical Co., Ltd., Otsuka Pharmaceutical Co., Ltd., and Kowa Company, Ltd. within the past five years. Dr. Hiroshi Horiguchi has received research funding from Alcon Japan Ltd. within the past five years. These relationships are unrelated to the present study. There are no patents, products in development or marketed products associated with this research to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials. The authors declare no other competing interests.