Prevalence of double heterozygotes of HbE and α-thal 1 (SEA) type in pregnancies and their partners that received antenatal care at Chiangrai Prachanukroh Hospital and reevaluated the cut-offs for differentiation

Prapapun Leckngam; Phanida Wamontree; Tapanut Chuaykarn

doi:10.1371/journal.pone.0333761

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Open Access

Peer-reviewed

Research Article

Prevalence of double heterozygotes of HbE and α-thal 1 (SEA) type in pregnancies and their partners that received antenatal care at Chiangrai Prachanukroh Hospital and reevaluated the cut-offs for differentiation

Prapapun Leckngam ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

* E-mail: prapapun.lec@mfu.co.th

Affiliations School of Health Science, Mae Fah Luang University, Chiangrai, Thailand, Biomedical Technology Research Group for Vulnerable Populations, Mae Fah Luang University, Chiangrai, Thailand

https://orcid.org/0009-0002-9190-3944

⨯
Phanida Wamontree,

Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – original draft

Affiliation School of Integrative Medicine, Mae Fah Luang University, Chiangrai, Thailand
⨯
Tapanut Chuaykarn

Roles Conceptualization, Data curation, Formal analysis, Resources, Validation, Writing – original draft

Affiliation Antenatal Care Clinic, Chiangrai Prachanukroh Hospital, Chiangrai Thailand
⨯

Prevalence of double heterozygotes of HbE and α-thal 1 (SEA) type in pregnancies and their partners that received antenatal care at Chiangrai Prachanukroh Hospital and reevaluated the cut-offs for differentiation

Prapapun Leckngam,
Phanida Wamontree,
Tapanut Chuaykarn

Published: October 7, 2025
https://doi.org/10.1371/journal.pone.0333761

About the Authors

Prapapun Leckngam

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

* E-mail: prapapun.lec@mfu.co.th

Affiliations School of Health Science, Mae Fah Luang University, Chiangrai, Thailand, Biomedical Technology Research Group for Vulnerable Populations, Mae Fah Luang University, Chiangrai, Thailand

https://orcid.org/0009-0002-9190-3944

Phanida Wamontree

Roles Conceptualization, Data curation, Formal analysis, Validation, Writing – original draft

Affiliation School of Integrative Medicine, Mae Fah Luang University, Chiangrai, Thailand

Tapanut Chuaykarn

Roles Conceptualization, Data curation, Formal analysis, Resources, Validation, Writing – original draft

Affiliation Antenatal Care Clinic, Chiangrai Prachanukroh Hospital, Chiangrai Thailand

Competing Interests

The authors have declared that no competing interests exist.

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Heterozygosity
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Hemoglobin
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Alpha-thalassemia
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Pregnancy
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Hematology
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Thalassemia
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Blood counts
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Antenatal care
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