About the Authors

Ruben Heuer

Roles Conceptualization, Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

ruben.heuer@charite.de

‡ These authors share first authorship on this work.

Affiliation Division of Evidence-based Medicine (dEBM), Department of Dermatology, Venereology und Allergy, Charité - University Medicine Berlin, Corporate Member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany

Maren Paulmann

Roles Conceptualization, Data curation, Writing – review & editing

‡ These authors share first authorship on this work.

Affiliation Dokumentationszentrum schwerer Hautreaktionen (dZh), Department of Dermatology Medical Center, University of Freiburg, Freiburg, Germany

Maja Mockenhaupt

Roles Data curation, Funding acquisition, Writing – review & editing

Affiliation Dokumentationszentrum schwerer Hautreaktionen (dZh), Department of Dermatology Medical Center, University of Freiburg, Freiburg, Germany

Alexander Nast

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

Affiliation Division of Evidence-based Medicine (dEBM), Department of Dermatology, Venereology und Allergy, Charité - University Medicine Berlin, Corporate Member of Free University of Berlin, Humboldt University of Berlin, and Berlin Institute of Health, Berlin, Germany

Competing Interests

Conflict of Interest Disclosures: Maja Mockenhaupt reported serving on a scientific advisory board for Boehringer Ingelheim and Merck AG; the German Registry on severe skin reactions (dZh) received financial support for research (through contracts with the University of Freiburg) from several pharmaceutical companies for the provision of safety information related to drugs manufactured or distributed by them. Ruben Heuer, Maren Paulmann, and Alexander Nast declare no potential conflicts of interest involving the work under consideration for publication. This does not alter our adherence to PLOS ONE policies on sharing data and materials.