Dissecting the shared genetic architecture of bipolar disorder, major depressive disorder, and attention-deficit hyperactivity disorder

Christopher Lawrence; Thomas Folkmann Hansen

doi:10.1371/journal.pone.0333571

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Open Access

Peer-reviewed

Research Article

Dissecting the shared genetic architecture of bipolar disorder, major depressive disorder, and attention-deficit hyperactivity disorder

Christopher Lawrence ,

Contributed equally to this work with: Christopher Lawrence, Thomas Folkmann Hansen

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: chrislaw133@gmail.com

Affiliations Wake Forest Department of Biology, Winston-Salem, North Carolina, United States of America, Information Systems and Wake Forest University. WFU High Performance Computing Facility, Winston-Salem, North Carolina, United States of America, DIS Research, Copenhagen, Denmark

https://orcid.org/0009-0001-2629-6378

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Thomas Folkmann Hansen

Contributed equally to this work with: Christopher Lawrence, Thomas Folkmann Hansen

Roles Conceptualization, Methodology, Software, Supervision

Affiliations DIS Research, Copenhagen, Denmark, Neurogenomic, Translational Research Centre, Copenhagen University Hospital, Glostrup, Denmark
⨯

Dissecting the shared genetic architecture of bipolar disorder, major depressive disorder, and attention-deficit hyperactivity disorder

Christopher Lawrence,
Thomas Folkmann Hansen

Published: February 23, 2026
https://doi.org/10.1371/journal.pone.0333571

About the Authors

Christopher Lawrence

Contributed equally to this work with: Christopher Lawrence, Thomas Folkmann Hansen

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: chrislaw133@gmail.com

Affiliations Wake Forest Department of Biology, Winston-Salem, North Carolina, United States of America, Information Systems and Wake Forest University. WFU High Performance Computing Facility, Winston-Salem, North Carolina, United States of America, DIS Research, Copenhagen, Denmark

https://orcid.org/0009-0001-2629-6378

Thomas Folkmann Hansen

Contributed equally to this work with: Christopher Lawrence, Thomas Folkmann Hansen

Roles Conceptualization, Methodology, Software, Supervision

Affiliations DIS Research, Copenhagen, Denmark, Neurogenomic, Translational Research Centre, Copenhagen University Hospital, Glostrup, Denmark

Competing Interests

The authors have declared that no competing interests exist.

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ADHD
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Genetics
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Dopaminergics
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Depression
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Neurons
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Single nucleotide polymorphisms
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Magma
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Genome-wide association studies
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