Quantitative modeling of mortality patterns in dogs exposed to alpha particle emitting radionuclides: Insights from competing risks and causal inference machine learning

Eric Wang; Igor Shuryak; David J. Brenner

doi:10.1371/journal.pone.0328082

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Open Access

Peer-reviewed

Research Article

Quantitative modeling of mortality patterns in dogs exposed to alpha particle emitting radionuclides: Insights from competing risks and causal inference machine learning

Eric Wang ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ew2717@cumc.columbia.edu

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America

https://orcid.org/0000-0002-5963-1670

⨯
Igor Shuryak,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America
⨯
David J. Brenner

Roles Resources, Supervision, Writing – review & editing

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America
⨯

Quantitative modeling of mortality patterns in dogs exposed to alpha particle emitting radionuclides: Insights from competing risks and causal inference machine learning

Eric Wang,
Igor Shuryak,
David J. Brenner

Published: July 21, 2025
https://doi.org/10.1371/journal.pone.0328082

About the Authors

Eric Wang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ew2717@cumc.columbia.edu

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America

https://orcid.org/0000-0002-5963-1670

Igor Shuryak

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America

David J. Brenner

Roles Resources, Supervision, Writing – review & editing

Affiliation Center for Radiological Research, Department of Radiation Oncology, Columbia University Irving Medical Center, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

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Cancers and neoplasms
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Cancer risk factors
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Cancer treatment
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Dogs
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Inhalation
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Radioactivity
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Alpha radiation
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Forests
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