About the Authors

Ralf Jäger

Roles Conceptualization, Writing – original draft

ralf.jaeger@increnovo.com

Affiliations Ingenious Ingredients L.P., Lewisville, TX, United States of America, Increnovo LLC, Whitefish Bay, WI, United States of America

Sidney Abou Sawan

Roles Writing – original draft

Affiliation Iovate Health Sciences International, Oakville, ON, Canada

Marco Orrú

Roles Conceptualization, Writing – review & editing

Affiliation Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, UT, United States of America

Grant M. Tinlsey

Roles Writing – review & editing

Affiliation Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, United States of America

Martin Purpura

Roles Conceptualization, Writing – review & editing

Affiliations Ingenious Ingredients L.P., Lewisville, TX, United States of America, Increnovo LLC, Whitefish Bay, WI, United States of America

Shawn D. Wells

Roles Conceptualization, Writing – review & editing

Affiliation Ingenious Ingredients L.P., Lewisville, TX, United States of America

Kylin Liao

Roles Conceptualization, Writing – review & editing

Affiliation Ingenious Ingredients L.P., Lewisville, TX, United States of America

Ashok Godavarthi

Roles Conceptualization, Writing – review & editing

Affiliation Radiant Research Services Pvt. Ltd., Bangalore, India

Competing Interests

RJ, MP, SDW and KL are researchers and principals of Ingenious Ingredients, the sponsor of the study, and inventors of a patent application for the use of 1-MX but have been involved in data collection or analysis. RJ, MP and SDW serve on the scientific advisory board and KL is the CEO of NNB Nutrition, the manufacturer of the 1-MX used in this study. AG is employed by Radiant Research Services Pvt. Ltd., and Radiant Research is a CRO who has received funding from Ingenious Ingredients to conduct this study. GMT provides consulting services, including statistical analysis and dietary supplement formulation, through Tinsley Consulting LLC but has no conflicts of interest related to the use of 1-MX. SA is employed by Iovate Health Sciences, a company selling dietary supplements. SA and MO declare no competing interests. This does not alter our adherence to PLOS ONE policies on sharing data and materials.