Relationship between protein conformational stability and its immunogenicity when administering antigens to mice using adjuvants—Analysis employed the CH2 domain in human antibodies

Open Access

Peer-reviewed

Research Article

Relationship between protein conformational stability and its immunogenicity when administering antigens to mice using adjuvants—Analysis employed the CH₂ domain in human antibodies

Kosuke Oyama

Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

Affiliation Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan

Tadashi Ueda

Roles Conceptualization, Project administration, Writing – review & editing

Affiliation Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan

The authors have declared that no competing interests exist.

Immunologic adjuvants
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Ribonucleases
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Antigens
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Immune response
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Alumni
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Antibody production
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Immune system proteins
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Lysozyme
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