About the Authors

Justin M. Gregory

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

justin.m.gregory.1@vumc.org

Affiliation Ian Burr Division of Pediatric Endocrinology and Diabetes, Vanderbilt University School of Medicine, Nashville, TN, United States of America

Guillaume Kraft

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Chiara Dalla Man

Roles Formal analysis, Methodology, Software, Writing – review & editing

Affiliation Department of Information Engineering, University of Padova, Padova, Italy

James C. Slaughter

Roles Formal analysis, Methodology, Software, Writing – review & editing

Affiliation Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States of America

Melanie F. Scott

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Jon R. Hastings

Roles Investigation, Project administration, Writing – review & editing

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Dale S. Edgerton

Roles Formal analysis, Methodology, Writing – review & editing

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Mary C. Moore

Roles Conceptualization, Formal analysis, Investigation, Methodology

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Alan D. Cherrington

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN United States of America

Competing Interests

Justin Gregory has served as an advisory board member for Sanofi, Eli Lilly, Medtronic, Dompe, vTv Therapeutics, and Mannkind Corporation and in data and safety monitoring roles for vTv Therapeutics and Medtronic. Alan Cherrington is a scientific advisor, consultant, and holds stock in Fractyl Laboratories. He also holds stock in Metavention. The other authors have declared that no competing interests exist. This does not alter our adherence to PLOS ONE policies on sharing data and materials.