About the Authors
- Jesyin Lai
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Contributed equally to this work with: Jesyin Lai, Ping Zou
Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
* E-mail: jesyin.lai@stjude.org (JL); ranganatha.sitaram@stjude.org (RS)
Affiliation Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Ping Zou
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Contributed equally to this work with: Jesyin Lai, Ping Zou
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Josue L. Dalboni da Rocha
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Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Andrew M. Heitzer
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Roles Conceptualization, Methodology, Writing – review & editing
Affiliation Department of Psychology and Biobehavioral Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Tushar Patni
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Roles Formal analysis, Writing – review & editing
Affiliation Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Yimei Li
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Roles Formal analysis, Writing – review & editing
Affiliation Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Matthew A. Scoggins
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Roles Conceptualization, Methodology, Writing – review & editing
Affiliation Department of Psychology and Biobehavioral Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Akshay Sharma
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Roles Conceptualization, Methodology, Writing – review & editing
Affiliation Department of Bone Marrow Transplantation & Cellular Therapy, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Winfred C. Wang
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Roles Conceptualization, Methodology, Writing – review & editing
Affiliation Department of Hematology, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Kathleen J. Helton
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Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing
Affiliation Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
- Ranganatha Sitaram
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Roles Conceptualization, Project administration, Supervision, Writing – review & editing
* E-mail: jesyin.lai@stjude.org (JL); ranganatha.sitaram@stjude.org (RS)
Affiliation Department of Diagnostic Imaging, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
Competing Interests
Dr. Akshay Sharma has received consultant fees from Spotlight Therapeutics, Medexus Inc., Vertex Pharmaceuticals, Sangamo Therapeutics, and Editas Medicine. He has also received research funding from CRISPR Therapeutics and honoraria from Vindico Medical Education. Dr. Sharma is the St. Jude site principal investigator of clinical trials for genome editing for SCD sponsored by Vertex Pharmaceuticals/CRISPR Therapeutics (NCT03745287), Novartis Pharmaceuticals (NCT04443907), and Beam Therapeutics (NCT05456880). The industry sponsors provide funding for the clinical trial, which includes salary support paid to our institution. Dr. Sharma has no direct financial interest in these therapies. Dr. Andrew M. Heitzer has received consulting fees from Global Blood Therapeutics. Neither Dr. Sharma nor Dr. Heitzer is an employee of any commercial entity. All other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. This does not alter our adherence to PLoS ONE policies on sharing data and materials.