About the Authors

Jon B. Toledo

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

habes@uthscsa.edu (MH); jtoledo@houstonmethodist.org (JBT)

Affiliations Department of Neurology, University of Florida College of Medicine, Gainesville, Florida, United States of America, Department of Neurology Houston Methodist Hospital, Houston, Texas, United States of America

Tanweer Rashid

Roles Formal analysis, Methodology, Software, Writing – review & editing

Affiliation Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America

Hangfan Liu

Roles Methodology, Software, Writing – review & editing

Affiliations Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Lenore Launer

Roles Writing – review & editing

Affiliation Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America

Leslie M. Shaw

Roles Writing – review & editing

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Susan R. Heckbert

Roles Writing – review & editing

Affiliation Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America

Michael Weiner

Roles Writing – review & editing

Affiliations Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America, Department of Radiology, University of California, San Francisco, California, United States of America, Department of Medicine, University of California, San Francisco, California, United States of America, Department of Psychiatry, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

Sudha Seshadri

Roles Writing – review & editing

Affiliation Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, United States of America

Mohamad Habes

Roles Conceptualization, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

habes@uthscsa.edu (MH); jtoledo@houstonmethodist.org (JBT)

Affiliations Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, United States of America

for the Alzheimer’s Disease Neuroimaging Initiative

Membership of the Alzheimer’s Disease Neuroimaging Initiative Group is listed in the Acknowledgments.

Competing Interests

Dr. Shaw provides quality control oversight for the Roche Electrosys immunoassay platform as part of the ADNI-3 study. Dr. Weiner has served on the Scientific Advisory Boards for Alzheon, Inc., Accera, Merck, Nestle (Nolan), PCORI (PPRN), Eli Lilly, Delfino Logic Ltd. (for Merck), Dolby Ventures, Brain Health Registry, and ADNI. He served on the editorial boards for Alzheimer’s & Dementia and MRI. He has provided consulting and/or acted as a speaker/lecturer to Synarc, Pfizer, Accera, Inc., Alzheimer’s Drug Discovery Foundation (ADDF), Merck, BioClinica, Eli Lilly, Howard University, Guidepoint, Denali Therapeutics, Nestle/Nestec, GLG Research, Atheneum Partners, BIONEST Partners, American Academy of Neurology (AAN), and Society for Nuclear Medicine and Molecular Imaging (SNMMI). This does not alter our adherence to PLOS ONE policies on sharing data and materials. Other authors report no competing interests.