About the Authors

Hasan Raza Mohammad

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Rachael Gooberman-Hill

Roles Writing – review & editing

Affiliations Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom, National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, United Kingdom

Antonella Delmestri

Roles Writing – review & editing

Affiliations Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom, Nuffield Department of Orthopaedics, Centre for Statistics in Medicine, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

John Broomfield

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Rita Patel

Roles Writing – review & editing

Affiliation Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom

Joerg Huber

Roles Writing – review & editing

Affiliation Department of Orthopedics, Stadtspital Triemli, Zurich, Switzerland

Cesar Garriga

Roles Writing – review & editing

Affiliations Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom

Christopher Eccleston

Roles Writing – review & editing

Affiliation Department for Health, Centre for Pain Research, University of Bath, Bath, United Kingdom

Rafael Pinedo-Villanueva

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Tamer T. Malak

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Nigel Arden

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Andrew Price

Roles Writing – review & editing

Affiliation Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Vikki Wylde

Roles Writing – review & editing

Affiliations Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom, National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, United Kingdom

Tim J. Peters

Roles Writing – review & editing

Affiliation Population Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom

Ashley W. Blom

Roles Writing – review & editing

Affiliations Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom, National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, United Kingdom

Andrew Judge

Roles Writing – review & editing

Andrew.judge@bristol.ac.uk

Affiliations Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom, Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning and Research Building, Bristol, United Kingdom, National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and University of Bristol, Bristol, United Kingdom, Nuffield Department of Orthopaedics, Centre for Statistics in Medicine, Rheumatology and Musculoskeletal Sciences, Nuffield Orthopaedic Centre, University of Oxford, Oxford, United Kingdom

Competing Interests

All authors have completed the Unified Competing Interest form at www.icmje.org/coi_disclosure.pdf and declare: AJ reports grants from NIHR PGfAR, during the conduct of the study; personal fees from Freshfields Bruckhaus Derringer, personal fees from Anthera Pharmaceuticals Ltd, outside the submitted work; RGH reports grants from NIHR PGfAR, during the conduct of the study. HRM reports grants from Royal College of Surgeons Research Fellowship, outside the submitted work; RPV reports research funding from UK-NIHR, Kyowa Kirin Services, International Osteoporosis Foundation, and lecture fees and/or consulting honoraria from Amgen, UCB, Kyowa Kirin Services, and Mereo Biopharma, all outside of the scope of this study; NA reports personal fees from Pfizer/Lilly, personal fees from Bristows LLP, grants from Merck Grant, outside the submitted work; VW reports grants from NIHR, during the conduct of the study; TJP reports grants from UK NIHR Programme Grant for Applied Research, during the conduct of the study. All other authors declare no conflicts of interest. This does not alter our adherence to PLOS ONE policies on sharing data and materials.