About the Authors

Caryn Cloer

Roles Formal analysis, Methodology

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Laila Roudsari

Roles Formal analysis

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Lauren Rochelle

Roles Data curation, Methodology

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Timothy Petrie

Roles Data curation, Formal analysis

Affiliation Draper, Cambridge, Massachusetts, United States of America

Michaela Welch

Roles Data curation

Affiliation Draper, Cambridge, Massachusetts, United States of America

Joseph Charest

Roles Data curation

Affiliation Draper, Cambridge, Massachusetts, United States of America

Kelly Tan

Roles Data curation

Affiliation Draper, Cambridge, Massachusetts, United States of America

Li Fugang

Roles Supervision

Affiliation HD Biosciences, Shanghai, China

Thomas Petersen

Roles Supervision

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Roger Ilagan

Roles Supervision

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Sarah Hogan

Roles Conceptualization, Formal analysis, Visualization

sseiler@unither.com

Affiliation Department of Regenerative Medicine, United Therapeutics Corporation, Durham, North Carolina, United States of America

Competing Interests

The authors of this manuscript have read the journal’s policy and have the following competing interests: CMC, LCR, LKR, RMI, THP, and SEH are paid employees of United Therapeutics. TAP, MW, JC and KT are employees of Draper, and LF is an employee of HD Biosciences. The authors further declare an associated nonprovisional patent (62/943,555) covering the use of extracellular vesicles in the treatment of ALI. Neither United Therapeutics, Draper, nor HD Biosciences commercial affiliation nor patent filing alters our adherence to PLOS ONE policies on sharing data and materials.