About the Authors

Yuan Sun

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft

ys546@cam.ac.uk

Affiliation Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Holly Pavey

Roles Writing – review & editing

Affiliation Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Ian Wilkinson

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Marie Fisk

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Division of Experimental Medicine and Immunotherapeutics, Department of Medicine, University of Cambridge, Cambridge, United Kingdom

Competing Interests

We have no conflicts of interest to disclose. Dr Marie Fisk holds a Clinical Lectureship at the University of Cambridge which is supported jointly by the University of Cambridge Experimental Medicine Training Initiative (EMI) programme in partnership with AstraZeneca (EMI-AZ) and Cambridge University Hospitals NHS Foundation Trust. The funding from AstraZeneca does not represent any financial or non-financial competing interests for Dr Fisk. This does not alter our adherence to PLOS ONE policies on sharing data and materials.