About the Authors

Declan Williams

Contributed equally to this work with: Declan Williams, Mohadeseh Mehrabian, Hamza Arshad

Roles Data curation, Investigation, Methodology, Software, Validation, Visualization, Writing – review & editing

Affiliation Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada

Mohadeseh Mehrabian

Contributed equally to this work with: Declan Williams, Mohadeseh Mehrabian, Hamza Arshad

Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Hamza Arshad

Contributed equally to this work with: Declan Williams, Mohadeseh Mehrabian, Hamza Arshad

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Shehab Eid

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Christopher Sackmann

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliation Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada

Wenda Zhao

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Xinzhu Wang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Farinaz Ghodrati

Roles Investigation, Methodology, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Claire E. Verkuyl

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

Affiliation Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada

Joel C. Watts

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Gerold Schmitt-Ulms

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft

g.schmittulms@utoronto.ca

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada

Competing Interests

DW, MM and GS declare the filing of a provisional patent for the treatment of prion diseases that builds on the relationship between NKAs and PrP.