About the Authors

Ying Cui

Contributed equally to this work with: Ying Cui, Hae-Suk Kim

Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Republic of Korea, Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Republic of Korea

Hae-Suk Kim

Contributed equally to this work with: Ying Cui, Hae-Suk Kim

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation Theragen Bio Co., Ltd, Seongnam-si, Republic of Korea

Eunae Sandra Cho

Roles Resources

Affiliations Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Republic of Korea, Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Republic of Korea

Dawool Han

Roles Resources

Affiliations Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Republic of Korea, Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Republic of Korea

Jung Ah Park

Roles Formal analysis, Software

Affiliation Theragen Bio Co., Ltd, Seongnam-si, Republic of Korea

Ju Yeong Park

Roles Formal analysis, Software

Affiliation Theragen Bio Co., Ltd, Seongnam-si, Republic of Korea

Woong Nam

Roles Resources

Affiliation Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Republic of Korea

Hyung Jun Kim

Roles Resources

Affiliation Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Republic of Korea

In-Ho Cha

Roles Resources

Affiliation Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Republic of Korea

Yong Hoon Cha

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

omfscha@yuhs.ac

Affiliations Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Republic of Korea, Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Republic of Korea

Competing Interests

HSK, JYP, and JAP, who are employees of Theragen Bio, solely contribute their scientific expertise and knowledge to conduct next-generation sequencing and bioinformatics analysis for this study. They do not have any competing interests. Also, I would like to declare that Theragen Bio did not provide any funding for this study and does not alter my adherence to PLOS ONE policies on sharing data and materials.