About the Authors

Junhyung Kim

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

Seongsung Kwak

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

Affiliations Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea, Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea

Mi-Sun Park

Roles Data curation, Investigation, Methodology, Project administration, Validation, Writing – review & editing

Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

Chang-Hoon Rhee

Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – review & editing

Affiliation Osong R&D Center, Medytox Inc., Cheongju-si, Chungcheongbuk-do, Korea

Gi-Hyeok Yang

Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – review & editing

Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

Jangmi Lee

Roles Data curation, Writing – review & editing

Affiliation Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Songpa-gu, Seoul, Korea

Woo-Chan Son

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

whkang@medytox.com (WhK); wcson32@hanmail.net (WCS)

‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

Affiliation Department of Pathology, Asan Medical Center, Songpa-gu, Seoul, Korea

Won-ho Kang

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

whkang@medytox.com (WhK); wcson32@hanmail.net (WCS)

‡ JK and SK contributed equally to this work and served as co-first authors. WhK and WCS also contributed equally to this work and served as corresponding authors.

Affiliation Gwanggyo R&D Center, Medytox Inc., Suwon-si, Gyeonggi-do, Korea

Competing Interests

The authors have declared that no competing interests exist. Furthermore, the authors [JK, SK, MSP, CHR, GHY, WhK] employed by a commercial company, Medytox Inc., confirm that this commercial affiliation does not alter their adherence to PLOS ONE policies on sharing data and materials.