5-aza-2’-deoxycytidine induces apoptosis and inhibits tumour growth in vivo of FaDu cells, a specific HPVnegative HNSCC cell line

Reem Miari; Naiel Azzam; Rinat Bar-Shalom; Fuad Fares

doi:10.1371/journal.pone.0253756

Loading metrics

Open Access

Peer-reviewed

Research Article

5-aza-2’-deoxycytidine induces apoptosis and inhibits tumour growth in vivo of FaDu cells, a specific HPVnegative HNSCC cell line

Reem Miari,

Roles Data curation, Writing – original draft

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel
⨯
Naiel Azzam,

Roles Investigation

Affiliations Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel, MIGAL Galilee Research Institute, Kiryat Shmona, Israel
⨯
Rinat Bar-Shalom,

Roles Investigation

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel
⨯
Fuad Fares

Roles Supervision, Writing – review & editing

* E-mail: ffares@sci.haifa.ac.il

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel

https://orcid.org/0000-0002-4408-8847

⨯

5-aza-2’-deoxycytidine induces apoptosis and inhibits tumour growth in vivo of FaDu cells, a specific HPVnegative HNSCC cell line

Reem Miari,
Naiel Azzam,
Rinat Bar-Shalom,
Fuad Fares

Published: September 17, 2021
https://doi.org/10.1371/journal.pone.0253756

About the Authors

Reem Miari

Roles Data curation, Writing – original draft

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel

Naiel Azzam

Roles Investigation

Affiliations Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel, MIGAL Galilee Research Institute, Kiryat Shmona, Israel

Rinat Bar-Shalom

Roles Investigation

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel

Fuad Fares

Roles Supervision, Writing – review & editing

* E-mail: ffares@sci.haifa.ac.il

Affiliation Department of Human Biology, Faculty of Natural Science, University of Haifa, Haifa, Israel

https://orcid.org/0000-0002-4408-8847

Competing Interests

The authors have declared that no competing interests exist.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Head and neck cancers
Is the Subject Area "Head and neck cancers" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Cell cycle and cell division
Is the Subject Area "Cell cycle and cell division" applicable to this article?

Thanks for your feedback.
Head and neck squamous cell carcinoma
Is the Subject Area "Head and neck squamous cell carcinoma" applicable to this article?

Thanks for your feedback.
Nasopharyngeal carcinoma
Is the Subject Area "Nasopharyngeal carcinoma" applicable to this article?

Thanks for your feedback.