About the Authors

Monika Kozieł

Roles Conceptualization, Methodology, Writing – original draft

Affiliations Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, 1st Department of Cardiology and Angiology, Silesian Centre for Heart Diseases, Zabrze, Poland

Christine Teutsch

Roles Conceptualization, Investigation, Methodology, Resources, Writing – review & editing

Affiliation Department of Clinical Development and Medical Affairs, Therapeutic Area Cardiometabolism, Boehringer Ingelheim International GmbH, Ingelheim, Germany

Jonathan L. Halperin

Roles Conceptualization, Methodology, Validation, Writing – review & editing

Affiliation Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Kenneth J. Rothman

Roles Conceptualization, Methodology, Validation, Writing – review & editing

Affiliation RTI Health Solutions, Research Triangle Park, North Carolina, United States of America

Hans-Christoph Diener

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany

Chang-Sheng Ma

Roles Conceptualization, Writing – review & editing

Affiliation Cardiology Department, Atrial Fibrillation Center, Beijing AnZhen Hospital, Capital Medical University, Beijing, China

Sabrina Marler

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Biostatistics and Data Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, United States of America

Shihai Lu

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation Biostatistics and Data Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, United States of America

Venkatesh K. Gurusamy

Roles Investigation, Resources, Software, Writing – review & editing

Affiliation Global Epidemiology, Boehringer Ingelheim International GmbH, Ingelheim, Germany

Menno V. Huisman

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands

Gregory Y. H. Lip

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

gregory.lip@liverpool.ac.uk

Affiliations Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, 1st Department of Cardiology and Angiology, Silesian Centre for Heart Diseases, Zabrze, Poland, Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

on behalf of the GLORIA-AF Investigators

Membership of the GLORIA-AF Investigators Group is listed in the Acknowledgments.

Competing Interests

The authors have read the journal’s policy and have the following competing interests: Dr. Teutsch, Sabrina Marler, and Venkatesh K. Gurusamy are paid employees of Boehringer Ingelheim. Dr. Lu was a paid employee of Boehringer Ingelheim at the time that the manuscript was written. Professor Halperin has engaged in consulting activities for Boehringer Ingelheim and advisory activities involving anticoagulants, and he is a member of the Executive Steering Committee of the GLORIA-AF Registry. Over the past 3 years, Professor Diener received honoraria for participation in clinical trials, contribution to advisory boards, or oral presentations from: Abbott, Bayer Vital, Bristol-Myers Squibb, Boehringer Ingelheim, Daiichi Sankyo, Medtronic, Pfizer, Portola, Sanofi-Aventis, and WebMD Global. Financial support for research projects was provided by Boehringer Ingelheim. He received research grants from the German Research Council (DFG), German Ministry of Education and Research (BMBF), European Union, NIH, Bertelsmann Foundation, and Heinz-Nixdorf Foundation. Professor Ma received honoraria from Bristol-Myers Squibb, Pfizer, Johnson & Johnson, Boehringer Ingelheim, Bayer, and AstraZeneca for giving lectures. Professor Huisman reports grants from ZonMW Dutch Healthcare Fund, grants and personal fees from Boehringer Ingelheim, Pfizer/Bristol-Myers Squibb, Bayer Health Care, Aspen, Daiichi Sankyo, outside the submitted work. Professor Lip has been a consultant for Bayer/Janssen, Bristol-Myers Squibb/Pfizer, Medtronic, Boehringer Ingelheim, Novartis, Verseon, and Daiichi Sankyo. He has been a speaker for Bayer, Bristol-Myers Squibb/Pfizer, Medtronic, Boehringer Ingelheim, and Daiichi Sankyo. No fees directly received personally. These competing interests do not alter our adherence to PLOS ONE policies on sharing data and materials. There are no patents, products in development or marketed products associated with this research to declare. Dr Kozieł and Professor Rothman declare no competing interests.