About the Authors

Jason A. West

Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

Affiliation Fractyl Laboratories Inc, Lexington, MA, United States of America

Anastasia Tsakmaki

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Diabetes Research Group, School of Life Course Sciences, Faculty of Life Science and Medicine, King’s College London, London, England, United Kingdom

Soumitra S. Ghosh

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Doon Associates LLC, San Diego, CA, United States of America

David G. Parkes

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation DGP Scientific Inc, San Diego, CA, United States of America

Rikke V. Grønlund

Roles Investigation

Affiliation Gubra ApS, Hørsholm, Denmark

Philip J. Pedersen

Roles Conceptualization, Formal analysis, Investigation, Methodology

Affiliation Gubra ApS, Hørsholm, Denmark

David Maggs

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Current address: Becton Dickinson Technologies & Innovation, Raleigh-Durham, NC, United States of America

Affiliation Fractyl Laboratories Inc, Lexington, MA, United States of America

Harith Rajagopalan

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Fractyl Laboratories Inc, Lexington, MA, United States of America

Gavin A. Bewick

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

gavin.bewick@kcl.ac.uk

Affiliation Diabetes Research Group, School of Life Course Sciences, Faculty of Life Science and Medicine, King’s College London, London, England, United Kingdom

Competing Interests

The authors have read the journal’s policy and have the following competing interests: J.A.W. and H.R. are employees and shareholders of Fractyl Laboratories Inc. A.T. has received funding/grant support from the Juvenile Diabetes Research Foundation (JDRF). S.S.G. is an employee of Doon Associates and has received honorariums for consultancy from Fractyl Laboratories Inc. D.G.P. is an employee of DPB Scientific and has received honorariums for consultancy from Fractyl Laboratories Inc R.V.G. and P.J.P. are employees of Gubra ApS. D.M. is an ex-employee of Fractyl Laboratories Inc., is a current shareholder, and has received honorarium for consultancy from Fractyl Laboratories Inc. G.A.B. has received funding/grant support from the European Foundation for the Study of Diabetes and JDRF and honorarium for consultancy from Fractyl Laboratories Inc. This does not alter our adherence to PLOS ONE policies on the sharing of data and materials. There are no patents, products in development or marketed products associated with this research to declare.