Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms

Open Access

Peer-reviewed

Research Article

About the Authors

Jozsef Karman

Roles Conceptualization, Formal analysis, Visualization, Writing – original draft

Affiliation Cambridge Research Center, AbbVie, Cambridge, Massachusetts, United States of America

Jing Wang

Roles Formal analysis

Affiliation Cambridge Research Center, AbbVie, Cambridge, Massachusetts, United States of America

Corneliu Bodea

Roles Formal analysis, Funding acquisition

Affiliation Cambridge Research Center, AbbVie, Cambridge, Massachusetts, United States of America

Sherry Cao

Roles Conceptualization

Affiliation Cambridge Research Center, AbbVie, Cambridge, Massachusetts, United States of America

Marc C. Levesque

Roles Conceptualization, Writing – original draft

Affiliation Cambridge Research Center, AbbVie, Cambridge, Massachusetts, United States of America

All authors are employees of AbbVie, Inc. This does not alter our adherence to PLoS ONE policies on sharing data and materials.

Gene expression
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Fibroblasts
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Consensus clustering
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Epithelial cells
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Pulmonary fibrosis
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RNA sequencing
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Chemokines
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Pathogenesis
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