About the Authors

Taku Shigesawa

Contributed equally to this work with: Taku Shigesawa, Goki Suda

Roles Data curation, Investigation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Goki Suda

Contributed equally to this work with: Taku Shigesawa, Goki Suda

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

gsudgast@pop.med.hokudai.ac.jp

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Megumi Kimura

Roles Investigation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Osamu Maehara

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Yoshimasa Tokuchi

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Akinori Kubo

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Ren Yamada

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Ken Furuya

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Japan Community Health Care Organization (JCHO) Hokkaido Hospital, Hokkaido, Japan

Masaru Baba

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Japan Community Health Care Organization (JCHO) Hokkaido Hospital, Hokkaido, Japan

Takashi Kitagataya

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Kazuharu Suzuki

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Masatsugu Ohara

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Naoki Kawagishi

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Masato Nakai

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Takuya Sho

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Mitsuteru Natsuizaka

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Kenichi Morikawa

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Koji Ogawa

Roles Data curation

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Naoya Sakamoto

Roles Supervision

Affiliation Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Competing Interests

Professor Naoya Sakamoto has received lecture fees from Bristol Myers Squibb and Pharmaceutical K.K., grants and endowments from MSD, K.K., and Chugai Pharmaceutical Co., Ltd., and a research grant from Gilead Sciences Inc. and AbbVie GK. Dr. Goki Suda has received research grants from Merck & Co, Gilead Sciences Inc., and Bristol Myers Squibb. The other authors have no conflicts of interest to disclose. This does not alter our adherence to PLOS ONE policies on sharing data and materials.