About the Authors

Daniël Höhle

Contributed equally to this work with: Daniël Höhle, Kim van Rooij, Jos Bloemers, Adriaan Tuiten

Roles Conceptualization, Data curation, Methodology, Software, Writing – original draft, Writing – review & editing

daniel.hohle@gmail.com

Affiliation Emotional Brain B.V., Almere, The Netherlands

Kim van Rooij

Contributed equally to this work with: Daniël Höhle, Kim van Rooij, Jos Bloemers, Adriaan Tuiten

Roles Conceptualization, Writing – review & editing

Affiliations Emotional Brain B.V., Almere, The Netherlands, Utrecht Institute for Pharmaceutical Sciences and Rudolf Magnus Institute of Neuroscience, Utrecht University, Utrecht, The Netherlands

Jos Bloemers

Contributed equally to this work with: Daniël Höhle, Kim van Rooij, Jos Bloemers, Adriaan Tuiten

Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations Emotional Brain B.V., Almere, The Netherlands, Utrecht Institute for Pharmaceutical Sciences and Rudolf Magnus Institute of Neuroscience, Utrecht University, Utrecht, The Netherlands

James G. Pfaus

Roles Conceptualization, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Centro de Investigaciones Cerebrales, Xalapa, Mexico

Frits Michiels

Roles Conceptualization, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliation Chemistry and Life Sciences, V.O. Patients & Trademarks, Amsterdam, The Netherlands

Paddy Janssen

Roles Data curation, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliations Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center+, Maastricht, The Netherlands, Department of Hospital Pharmacy, VieCuri Medical Center Venlo, Venlo, The Netherlands

Eric Claassen

Roles Conceptualization, Writing – review & editing

‡ These authors also contributed equally to this work.

Affiliations Emotional Brain B.V., Almere, The Netherlands, Athena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Adriaan Tuiten

Contributed equally to this work with: Daniël Höhle, Kim van Rooij, Jos Bloemers, Adriaan Tuiten

Roles Conceptualization, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation Emotional Brain B.V., Almere, The Netherlands

Competing Interests

The funder provided support in the form of salaries for authors DH, KvR, JB, and AT; shares / share options for authors KvR, JB, EC and AT. FM, PJ and EC declare no competing interests. JP is on the advisory board of, and/or a consultant to Emotional Brain, IVIX Corp. (Russia), Palatin Technologies/AMAG Pharmaceuticals (USA), and Viscunis Pharmaceuticals (Canada). The funder has active patents related to T+B, T+S, and the tablets: P72581, P75176, P79099-00, P92182, FID681336, P111330. This does not alter our adherence to PLOS ONE policies on sharing data and materials.