About the Authors

Andreas A. Karlsson

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Swedish eScience Research Centre, Stockholm, Sweden

Shuang Hao

Roles Conceptualization, Methodology, Writing – review & editing

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Swedish eScience Research Centre, Stockholm, Sweden

Alexandra Jauhiainen

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation BioPharma Early Biometrics and Statistical Innovation, Data Science & AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

K. Miriam Elfström

Roles Methodology, Writing – review & editing

Affiliation Department of Laboratory Medicine, Karolinska University Hospital, Stockholm, Sweden

Lars Egevad

Roles Methodology, Writing – review & editing

Affiliation Department of Oncology-Pathology, Karolinska University Hospital, Stockholm, Sweden

Tobias Nordström

Roles Methodology, Writing – review & editing

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden

Emelie Heintz

Roles Conceptualization, Methodology, Writing – review & editing

Affiliation Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden

Mark S. Clements

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

mark.clements@ki.se

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Swedish eScience Research Centre, Stockholm, Sweden

Competing Interests

MC, TN and LE were investigators on the Stockholm3 trial. They and the other authors have no financial or any other conflicts of interest. Specifically, none of the authors are party to the intellectual property associated with the Stockholm3 test. Author AJ is a full time employee and shareholder of AstraZeneca. AstraZeneca provided support in the form of salary for author AJ, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The competing interests declared do not alter our adherence to PLOS ONE policies on sharing data and materials.