Optimal two-stage design of single arm Phase II clinical trials based on median event time test

Yeonhee Park

doi:10.1371/journal.pone.0246448

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Open Access

Peer-reviewed

Research Article

Optimal two-stage design of single arm Phase II clinical trials based on median event time test

Yeonhee Park

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ypark56@wisc.edu

Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, United States of America

https://orcid.org/0000-0001-9645-3407

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Optimal two-stage design of single arm Phase II clinical trials based on median event time test

Yeonhee Park

Published: February 8, 2021
https://doi.org/10.1371/journal.pone.0246448

About the Authors

Yeonhee Park

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ypark56@wisc.edu

Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, United States of America

https://orcid.org/0000-0001-9645-3407

Competing Interests

The authors have declared that no competing interests exist.

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Phase II clinical investigation
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Random variables
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Phase III clinical investigation
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Probability distribution
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Real numbers
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